“Isolator requirements for physiological conditions could be taken different ways depending on the process. In some cases, we are focused on including or having the ability to dock to an incubator. Sometimes we are concerned about particular aspects of the environment of the operation (e.g., VHP residual, humidity, temperature). Still other processes have seen advantages in operating an isolator as if it were a bioreactor during the open operations, with temperature, humidity, and gas control. – Herman & Erich Bozenhardt